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logologo

  • Home
  • About Us
  • About EpiDOSE
    • Key Facts
  • For Patients & Families
    • Follow Up Interview
  • For Investigators & EMS
  • For EDs
  • Resources
  • Glossary
  • News
  • Contact
  • Home
  • About Us
  • About EpiDOSE
    • Key Facts
  • For Patients & Families
    • Follow Up Interview
  • For Investigators & EMS
  • For EDs
  • Resources
  • Glossary
  • News
  • Contact

Resources

Videos

What is a sudden cardiac arrest?

Heart attack vs. cardiac arrest

Is there a treatment for sudden cardiac arrest?

What does an AED do?

How does CPR actually work?

Learn CPR in less than 90 seconds

Learn how to use an AED in less than 90 seconds

How to administer CPR during COVID-19

Links

Heart and Stroke Foundation of Canada

CanROC - Canadian Resuscitation Outcomes Consortium

Canadian Sudden Cardiac Arrest Network (C-SCAN)

Canadian SADS Foundation

Sudden Cardiac Arrest Foundation

The Hearts in Rhythm Organization (HiRO)

Canadian Red Cross CPR Training and Certifications

PARAMEDIC2 Trial

Relevant Publications

Long term outcomes of participants in the PARAMEDIC2 randomised trial of adrenaline in out-of-hospital cardiac arrest. Resuscitation.

Haywood KL, Ji C, Quinn T, Nolan JP, Deakin CD, Scomparin C, Lall R, Gates S, Long J, Regan S, Fothergill RT, Pocock H, Rees N, O’Shea L, Perkins GD. 021 Mar;160:84-93.

Epinephrine for Out-of-Hospital Cardiac Arrest: An Updated Systematic Review and Meta-Analysis. Crit Care Med.

Aves T, Chopra A, Patel M, Lin S. 2020 Feb;48(2):225-229.

The influence of time to adrenaline administration in the Paramedic 2 randomised controlled trial. Intensive Care Med

Perkins, G.D., Kenna, C., Ji, C. et al. 2020;46:426–436.

The CJEM Debate Series: #Epi – There is no place for the use of intravenous epinephrine as a standard component of cardiac arrest resuscitation care.

Welsford M, Buick JE, Drennan IR, Lin S, Atkinson. PR2019;21(3):324-329.

The effects of adrenaline in out of hospital cardiac arrest with shockable and non-shockable rhythms: Findings from the PACA and PARAMEDIC-2 randomised controlled trials.

Perkins GD, Kenna C, Ji C, Deakin C, Nolan JP, Quinn T, Fothergill R, Gunson I, Pocock H, Rees N, Charlton K, Finn J, Gates S, Lall R. Resuscitation. 2019.

Paramedic attitudes and experiences of enrolling patients into the PARAMEDIC-2 adrenaline trial: a qualitative survey within the London Ambulance Service.

Lazarus J, Iyer R, Fothergill RT. BMJ Open 2019;9:e025588.

Interpreting Observational Data on Adrenaline in Cardiac Arrest is Complicated.

Lin S, Dorian P. Resuscitation. 2019;138:314-315.

Study of the effects of epinephrine on cerebral oxygenation and metabolism during cardiac arrest and resuscitation by hyperspectral near-infrared spectroscopy.

Nosrati R, Lin S, Ramadeen A, Mohindra R, Toronov V, Dorian P. Crit Care Med. 2019;47(4):e349-e357.

A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest.

Perkins GD, Ji C, Deakin CD, et al. N Engl J Med 2018;379:711-21.

The role of adrenaline in cardiopulmonary resuscitation.

Gough, C.J.R., Nolan, J.P. Crit Care. 2018;22:139.

Prehospital epinephrine use and survival among patients with out-of-hospital cardiac arrest.

Hagihara A, Hasegawa M, Abe T, Nagata T, Wakata Y, Miyazaki S. JAMA 2012;307:1161-8.

Epinephrine In Cardiac Arrest: A Randomized, Multicenter, Double-blinded, Placebo-Controlled Experimental Trial.

Lin S SM, Dorian P, Fink S, Halperin H, Kiss A, Koller A, McCracken B, Morrison L, Neumar R, Niemann J, Ramadeen A, Salcido D, Tiba M, Youngquist S, Zviman M, Menegazzi J. Circulation 2015;132:A10437.

Adrenaline for out-of-hospital cardiac arrest resuscitation: a systematic review and meta-analysis of randomised controlled trials.

Lin S, Callaway CW, Shah PS, Wagner JD, Beyene J, Ziegler CP, Morrison LJ. Resuscitation. 2014;85(6):732-40.

Wide variability in drug use in out-of-hospital cardiac arrest: a report from the resuscitation outcomes consortium.

Glover BM, Brown SP, Morrison L, et al. Resuscitation. 2012;83:1324-30.

A randomized trial of drug route in out-of-hospital cardiac arrest.

Couper K, Ji C, Fothergill RT, Nolan JP, Long JB, Mason JM, et al. N Engl J Med. 2024;391(5):e104.

The way to a patient’s heart – vascular access in cardiac arrest.

Nielsen N. N Engl J Med. 2024;391(5):e107.

EpiDOSE at St. Michael’s Hospital

30 Bond Street Toronto, ON, Canada M5B 1W8

Telephone: 416-864-6060

Email: epidose@unityhealth.to

Congrats to @essexwindsorems for enrolling their f Congrats to @essexwindsorems for enrolling their first #EpiDOSE patient! 🎉
Congrats to @essexwindsorems on successfully launc Congrats to @essexwindsorems on successfully launching #EpiDOSE today! 🎉
Congratulations @superiornorthems for officially l Congratulations @superiornorthems for officially launching the #EpiDOSE trial today! 🎉🎉
Congratulations! @london_paramedics_147 joined #Ep Congratulations! @london_paramedics_147 joined #EpiDOSE and officially enrolled their first patient on their first day! 🎉 Way to go!
Congratulations! 🎉 Earlier this year, @haltonpa Congratulations! 🎉 Earlier this year, @haltonparamedicunion @bc_ehs and @ottawa_paramedic_service all successfully transitioned from study drug kits to our new randomization envelopes! #EpiDOSE
As of earlier this year, the #EpiDOSE trial has of As of earlier this year, the #EpiDOSE trial has officially switched over to using randomization kits! Randomization kits no longer include study drug, and medics are asked to use their own clinical supply instead.
EpiDOSE has now enrolled a total of 137 participan EpiDOSE has now enrolled a total of 137 participants! #EpiDOSE
Our #Epi article was one the of 5 most downloaded Our #Epi article was one the of 5 most downloaded articles in the Canadian Journal of Emergency Medicine (CJEM) in 2019! 👏 #epidose #cjem
We’re blowing up on twitter! Make sure to follow We’re blowing up on twitter! Make sure to follow us if you haven’t done so already #EpiDOSE
Thank you to Professor Tom Quinn for his mention o Thank you to Professor Tom Quinn for his mention of #EpiDOSE in his presentation at the #ESCcongress #WCC2019 @europeansocietyofcardiology
Be sure to follow us on twitter for updates about Be sure to follow us on twitter for updates about the #epidose trial!
Heart attack vs. cardiac arrest. Know the differen Heart attack vs. cardiac arrest. Know the difference, it can save a life. #epidose
Wondering what sudden cardiac arrest is? Wonder no Wondering what sudden cardiac arrest is? Wonder no more. #epidose
Each year in Canada, there are over 40,000 people Each year in Canada, there are over 40,000 people who collapse from cardiac arrest. 8 in 10 cardiac arrests occur at home or in public places. However, only 1 in 10 survive cardiac arrests that happen outside of the hospital. #epidose
Hello and welcome to EpiDOSE 👋! The study that Hello and welcome to EpiDOSE 👋! The study that aims to evaluate optimal vs. standard doses of epinephrine in out of hospital cardiac arrest patients. Follow us along on our journey to make patient care better.
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